Scientific publications

PrintFriendly and PDF
  • List of scientific (peer reviewed) articles


Hescheler J., DETECTIVE – Suche nach Biomarkern zur Prognose der Langzeittoxizität, LABORWELT, 03/2011. Artcile is available here.


Vinken M, Pauwels M, Ates G, Vivier M, Vanhaecke T, Rogiers V., Screening of repeated dose toxicity data present in SCC(NF)P/SCCS safety evaluations of cosmetic ingredients, Arch Toxicol. 2012 Mar;86(3):405-12. doi: 10.1007/s00204-011-0769-z. Epub 2011 Oct 29. Article available here.


Seeliger C, Culmes M, Schyschka L, Yan X, Damm G, Wang Z, Kleeff J, Thasler WE, Hengstler J, Stöckle U, Ehnert S, Nussler AK, Decrease of global Methylation improves significantly hepatic Differentiation of Ad-MSCs: Possible future Application for Urea Detoxification, Cell Transplant. 2012 Apr 10. Abstract available here.


Heise T, Schug M, Storm D, Ellinger-Ziegelbauer H, Ahr HJ, Hellwig B, Rahnenfuhrer J, Ghallab A, Guenther G, Sisnaiske J, Reif R, Godoy P, Mielke H, Gundert-Remy U, Lampen A, Oberemm A, Hengstler JG, In vitro – in vivo correlation of gene expression, Curr Med Chem. 2012;19(11):1721-30. Abstract availabe here.


Vinken M, Landesmann B, Goumenou M, Vinken S, Shah I, Jaeschke H, Willett C, Whelan M, Rogiers V. Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury. Toxicol Sci. 2013 Nov;136(1):97-106. Abstract available here.


Vinken M. The adverse outcome pathway concept: a pragmatic tool in toxicology. Toxicology. 2013 Oct 4;312:158-65. Abstract available here.


Rodrigues RM, De Kock J, Branson S, Vinken M, Meganathan K, Chaudhari U, Sachinidis A, Govaere O, Roskams T, De Boe V, Vanhaecke T, Rogiers V, Human skin-derived stem cells as a novel source for in vitro hepatotoxicity screening of pharmaceuticals. Stem Cells Dev. 2014 Jan 1;23(1):44-55. Abstract available here.


Canovas-Jorda D, Louisse J, Pistollato F, Zagoura D, Bremer S. Regenerative toxicology: the role of stem cells in the development of chronic toxicities. Expert Opin Drug Metab Toxicol. 2014 Jan;10(1):39-50. Abstract available here.


Limonciel A, Jennings P. A review of the evidence that orchratoxin A is an Nrf2 inhibitor: implications for nephrotoxicity and renal carcinogenicity. Toxins (Basel). 2014 Jan 20;6(1):371-9. Abstract available here.


Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P. The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity. Arch Toxicol. 2014 Jun;88(6):1267-80. Abstract available here.


Pistollato F, Louisse J, Scelfo B, Mennecozzi M, Accordi B, Basso G, Gaspar JA, Zagoura D, Barilari M, Palosaari T, Sachinidis A, Bremer-Hoffmann S. Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relatio toneurotoxicity: effects of CREB pathway inhibition. Toxicol Appl Pharmacol. 2014 Oct 15;280(2):378-88. Abstract available here.


Madden JC, Rogiers V, Vinken M. Application of in silico and in vitro methods in the development of adverse outcome pathway contructs in wildlife. Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). Abstract is available here.